Bioactive Small Molecules
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Filtered Search Results
Medchemexpress LLC 4-Boc-2-oxopiperazine | 76003-29-7 | 200.23 | 500 G
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4-Boc-2-Oxopiperazine is a biochemical reagent primarily used as a biological material or organic compound for various life science research applications.
- Purity of 98.0%
- Appears as a white to off-white solid
- Molecular formula C9H16N2O3
- Soluble in DMSO at 25 mg/mL
- Store powder at -20°C for 3 years or 4°C for 2 years
- Store in solvent at -80°C for 6 months or -20°C for 1 month
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Selleck Chemical LLC Ripretinib S8757-10MM/1ML
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Ripretinib is an orally bioavailable switch pocket control inhibitor of wild-type and mutated forms of the tumor-associated antigens (TAA) mast/stem cell factor receptor (SCFR) Kit (c-Kit) and PDGFR-alpha with IC50 values of 4 nM 8 nM 18 nM 5 nM and 14 nM for WT Kit (c-Kit) V654A Kit (c-Kit) T670I Kit (c-Kit) D816H Kit (c-Kit) and D816V Kit (c-Kit) respectively
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Medchemexpress LLC ANIMAL-FREE IL-1 BET 10UG
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5000178067 ANIMAL-FREE IL-1 BET 10UG
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Medchemexpress LLC ANIMAL-FREE GM-CSF 50UG
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5000178247 ANIMAL-FREE GM-CSF 50UG
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Medchemexpress LLC DHH HUMAN HIS-GST 20UG
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5000178248 DHH HUMAN HIS-GST 20UG
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Medchemexpress LLC BC-1382 100MG
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5000210176 BC-1382 100MG
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TARGETMOL CHEMICALS INC GGTI 2147 5MG
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. GGTI 2147 decreased Rac1 activity down-regulated p65 expression and ameliorated OGD/R-induced neuronal apoptosis. purity: 99%
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Medchemexpress LLC HY-17563 500mg Medchemexpress, 2'-Deoxyguanosine CAS:961-07-9 Purity:>98%
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Medchemexpress, HY-17563 500mg 2'-Deoxyguanosine CAS:961-07-9 0 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC GNE-235 | 3036574-72-5 | C13H16N4O | 25 MG
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GNE-235 is a compound selective for the second bromodomain of PBRM1, with a KD of 0.28 ± 0.02 μM. It can be used for the evaluation of the cellular function of PBRM1.
- Selective for the second bromodomain of PBRM1
- KD of 0.28 ± 0.02 μM
- Useful for evaluating the cellular function of PBRM1
- Purity: 98.45%
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Medchemexpress LLC 2H-Indol-2-one, 5-[[(2,6-dichlorophenyl)methyl]sulfonyl]-3-[[3,5-dimethyl-4-[[(2R)-2-(1-pyrrolidinylmethyl)-1-pyrrolidinyl]carbonyl]-1H-pyrrol-2-yl]methylene]-1,3-dihydro-, (3Z)- | 477575-56-7 | 98.2% | 641.61 | 10 MG
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2H-Indol-2-one, 5-[[(2,6-dichlorophenyl)methyl]sulfonyl]-3-[[3,5-dimethyl-4-[[(2R)-2-(1-pyrrolidinylmethyl)-1-pyrrolidinyl]carbonyl]-1H-pyrrol-2-yl]methylene]-1,3-dihydro-, (3Z)- | 477575-56-7 | 98.2% | 641.61 | 10 MG
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Cayman Chemical 1R 2S2 3 4DIfluorophenyl 5mg
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An analytical reference standard categorized as a conformationally restricted phenethylamine; intended for research and forensic applications
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Cayman Chemical ANTIBODY TRAM-34 10mg
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A metabolite of propranolol
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Medchemexpress LLC Asperuloside | 14259-45-1 | MFCD31725921 | 414.36 | 20 MG
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Asperuloside is an iridoid isolated from Hedyotis diffusa, with anti-inflammatory activity. It inhibits inducible nitric oxide synthase (iNOS) and suppresses NF-κB and MAPK signaling pathways.
- Anti-inflammatory activity.
- Inhibits inducible nitric oxide synthase (iNOS).
- Suppresses NF-κB and MAPK signaling pathways.
- Inhibits productions of NO, PGE2, TNF-α and IL-6 in LPS-induced RAW 264.7 cells (In Vitro).
- Inhibits cell viability and induces ER stress-dependent apoptosis in leukemia cell lines (U937, HL-60, AML) (In Vitro).
- Reduces food intake, body weight, and adipose masses in rats consuming a high fat diet (HFD) (In Vivo).
- Inhibits tumor growth of U937 xenografts mice model (In Vivo).
- Relieves LPS-induced acute lung injury via inhibiting MAPK and NF-κB signaling in BALB/c mice (In Vivo).
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Cayman Chemical ANTIBODY ABP 688 5mg
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A non-competitive antagonist of mGluR5 (Ki = 3.5 nM in a radioligand binding assay using L(tk-) cell membranes expressing human receptors); binds at an allosteric binding site; selective for mGluR5 receptors over a panel of CNS G protein-coupled receptors, ion channels, and transporters at 10 μM; inhibits quisqualate-induced phosphoinositol accumulation in and glutamate-induced calcium release from L(tk-) cells expressing human mGluR5 (IC50s = 2.4 and 2.3 nM, respectively); radiolabeled forms have been used as PET tracers for in vivo imaging of mGluR5 receptors in rodents
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Cayman Chemical ANTIBODY BLU-554 5mg
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A potent inhibitor of recombinant FGFR4 (IC50 50 < 10 nM), a marker of FGFR4 inhibition, in MDA-MB453 cells
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